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β€Ž04_Data_QC/README.mdβ€Ž

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@@ -368,7 +368,7 @@ Usually, variants can be categorized into 3 groups based on their Minor Allele F
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!!! info "How to calculate Minor Allele Frequency (MAF)"
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Suppose the reference allele(REF) is A and the alternative allele(ALT) is B for a certain SNP. The posible genotypes are AA, AB and BB. In a population of N samples (2N alleles), $N = N_{AA} + 2 \times N_{AB} + N_{BB}$ :
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Suppose the reference allele(REF) is A and the alternative allele(ALT) is B for a certain SNP. The possible genotypes are AA, AB and BB. In a population of N samples (2N alleles), $N = N_{AA} + N_{AB} + N_{BB}$:
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- the number of A alleles: $N_A = 2 \times N_{AA} + N_{AB}$
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- the number of B alleles: $N_B = 2 \times N_{BB} + N_{AB}$

β€Ždocs/04_Data_QC.mdβ€Ž

Lines changed: 1 addition & 1 deletion
Original file line numberDiff line numberDiff line change
@@ -368,7 +368,7 @@ Usually, variants can be categorized into 3 groups based on their Minor Allele F
368368

369369
!!! info "How to calculate Minor Allele Frequency (MAF)"
370370

371-
Suppose the reference allele(REF) is A and the alternative allele(ALT) is B for a certain SNP. The posible genotypes are AA, AB and BB. In a population of N samples (2N alleles), $N = N_{AA} + 2 \times N_{AB} + N_{BB}$ :
371+
Suppose the reference allele(REF) is A and the alternative allele(ALT) is B for a certain SNP. The possible genotypes are AA, AB and BB. In a population of N samples (2N alleles), $N = N_{AA} + N_{AB} + N_{BB}$:
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- the number of A alleles: $N_A = 2 \times N_{AA} + N_{AB}$
374374
- the number of B alleles: $N_B = 2 \times N_{BB} + N_{AB}$

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