From https://bugs.python.org/issue23242#msg284930

The following script is used to reproduce the bug:

import asyncio

async def execute():
    process = await asyncio.create_subprocess_exec(
        "timeout", "0.1", "cat", "/dev/urandom", stdout=asyncio.subprocess.PIPE)

    while True:
        data = await process.stdout.read(65536)
        print('read %d bytes' % len(data))
        if data:
            await asyncio.sleep(0.3)
        else:
            break

asyncio.get_event_loop().run_until_complete(execute())

will produce following output and terminate with exception:

read 65536 bytes
read 65536 bytes
Traceback (most recent call last):
  File "read_subprocess.py", line 18, in <module>
    asyncio.get_event_loop().run_until_complete(execute())
  File "/usr/lib/python3.6/asyncio/base_events.py", line 466, in run_until_complete
    return future.result()
  File "read_subprocess.py", line 9, in execute
    data = await process.stdout.read(65536)
  File "/usr/lib/python3.6/asyncio/streams.py", line 634, in read
    self._maybe_resume_transport()
  File "/usr/lib/python3.6/asyncio/streams.py", line 402, in _maybe_resume_transport
    self._transport.resume_reading()
  File "/usr/lib/python3.6/asyncio/unix_events.py", line 401, in resume_reading
    self._loop._add_reader(self._fileno, self._read_ready)
AttributeError: 'NoneType' object has no attribute '_add_reader'

When the process exits https://github.com/python/asyncio/blob/master/asyncio/unix_events.py#L444 is called which sets this._loop = None
Next time read() is called on the pipe the above exception is thrown.
I have tried to fix this issue myself but would sometimes have read terminate too early and miss the last chunks of data.